张鹭，中国医学科学院输血研究所研究员、细胞与基因治疗研究中心课题组组长、博士生导师，中国医学科学院北京协和医学院准长聘教职引进人才。
2022年1月毕业于中国科学院大学（中国科学院长春应用化学研究所），获博士学位。2022-2024在长春应化所任特别研究助理并获得中科院特别研究助理择优资助项目，从事仿生（类酶、类细胞）催化材料与生物运载材料的研究，作为负责人承担国家自然科学基金青年基金，吉林省科技发展计划项目青年成长科技计划项目。2024年加入中国医学科学院输血研究所，担任研究员。课题组长期聚焦于基于新型核酸递送载体的细胞与基因治疗研究，血液细胞的工程化改造与转化应用研究，相关研究成果在Advanced Materials (2), Angewandte Chemie (3), JACS, PNAS, ACS Nano等杂志发表高水平论文28篇，总他引＞2000次（web of science），以第一/通讯作者（含共同）发表学术论文8篇总他引＞700次（web of science）。
研究方向：
1. 新型脂质纳米颗粒的开发；
2. 工程化NK细胞与血小板在重大疾病的免疫治疗与再生医学中的应用探索与机制研究；
3. 类酶材料与再生医学。
代表性论文：
- Lu Zhang, Yanjuan Sang, Zhenqi Liu, Wenjie Wang, Zhengwei Liu, Qingqing Deng, Yawen You, Jinsong Ren,* and Xiaogang Qu* Liquid Metal as Bioinspired and Unusual Modulator in Bioorthogonal Catalysis for Tumor Inhibition Therapy Angew. Chem. Int. Ed. 2023, e202218159
- Lu Zhang, Huan Wang,* Xiaogang Qu* Biosystem-Inspired Engineering of Nanozymes for Biomedical Applications Adv. Mater. 2023, 2211147
- Lu Zhang; Zhengwei Liu; Qingqing Deng; Yanjuan Sang; Jinsong Ren*; Xiaogang Qu* Nature-Inspired Construction of MOF@COF Nanozyme with Active Sites in Tailored Microenvironment and Pseudopodia-Like Surface for Enhanced Bacterial Inhibition, Angew. Chem. Int. Ed, 2020. 60: 3469-3474
- Wenjie Wang, Lu Zhang,* Zhenqi Liu, Yanjie Zhang, Jiawei Zhu, Mengmeng Liu, Jinsong Ren,* and Xiaogang Qu* Selective Methionine Pool Exhaustion Mediated by a Sequential Positioned MOF Nanotransformer for Intense Cancer Immunotherapy Adv. Mater. 2023, 2211866
- Yanjie Zhang, Lu Zhang*, Wenjie Wang, Qingqing Deng, Mengmeng Liu，Zitong Zhu，Hao Liu, Jinsong Ren* and Xiaogang Qu* A DNA-Gated and Self-Protected Bioorthogonal Catalyst for Nanozyme-Assisted Safe Cancer Therapy Angew. Chem. Int. Ed. 2023, e202306395
- Lu Zhang; Zhenzhen Wang; Yan Zhang; Fangfang Cao; Kai Dong; Jinsong Ren* and Xiaogang Qu* Erythrocyte Membrane Cloaked Metal−Organic Framework Nanoparticle as Biomimetic Nanoreactor for StarvationActivated Colon Cancer Therapy, ACS Nano, 2018. 12: 10201-10211
- Lu Zhang; Yan Zhang; Zhenzhen Wang; Fangfang Cao; Yanjuan Sang; Kai Dong; Fang Pu; Jinsong Ren* and Xiaogang Qu* Constructing metal–organic framework nanodots as bio-inspired artificial superoxide dismutase for alleviating endotoxemia, Mater. Horiz., 2019. 6: 1682-1687
- Wenjie Wang#; Lu Zhang#; Qingqing Deng; Zhenqi Liu; Jinsong Ren* and Xiaogang Qu* Yeast@MOF bioreactor as a tumor metabolic symbiosis disruptor for the potent inhibition of metabolically heterogeneous tumors, Nano Today, 2021. 42: 101331
邮箱：luzhang@pumc.edu.cn
